Wang J, Wu N, Zheng QF, Yan S, Lv C, Li SL, Yang Y. Evaluation of the 7th edition of the TNM classification in patients with resected esophageal squamous cell carcinoma. World J Gastroenterol 2014; 20(48): 18397-18403 [PMID: 25561808 DOI: 10.3748/wjg.v20.i48.18397]
Corresponding Author of This Article
Yue Yang, MD, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University School of Oncology, Beijing Cancer Hospital and Institute, 52 Fucheng Avenue, Haidian District, Beijing 100142, China. zlyangyue@bjmu.edu.cn
Research Domain of This Article
Oncology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Dec 28, 2014; 20(48): 18397-18403 Published online Dec 28, 2014. doi: 10.3748/wjg.v20.i48.18397
Evaluation of the 7th edition of the TNM classification in patients with resected esophageal squamous cell carcinoma
Jia Wang, Nan Wu, Qing-Feng Zheng, Shi Yan, Chao Lv, Shao-Lei Li, Yue Yang
Jia Wang, Nan Wu, Qing-Feng Zheng, Shi Yan, Chao Lv, Shao-Lei Li, Yue Yang, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing 100142, China
Author contributions: Wang J designed the study and wrote the manuscript; Wu N checked and edited the manuscript; Zheng QF, Yan S, Lv C and Li SL collected and settled the data; and Yang Y guided the design of this manuscript.
Correspondence to: Yue Yang, MD, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Department of Thoracic Surgery II, Peking University School of Oncology, Beijing Cancer Hospital and Institute, 52 Fucheng Avenue, Haidian District, Beijing 100142, China. zlyangyue@bjmu.edu.cn
Telephone: +86-10-88196568 Fax: +86-10-88196568
Received: September 8, 2014 Revised: October 19, 2014 Accepted: November 7, 2014 Published online: December 28, 2014 Processing time: 119 Days and 10.5 Hours
Core Tip
Core tip: The 7th edition of the Union for International Cancer Control (UICC) and the American Joint Committee on Cancer (AJCC) TNM staging system for esophageal and gastroesophageal junction (GEJ) cancer is the first data-driven staging system for esophageal and GEJ cancers. It is based on the Worldwide Esophageal Cancer Collaboration database, which includes 4627 patients from a large multi-institutional collaboration involving 13 institutions and a data period ranging from the 1970s to the 2000s. Therefore, the surgical procedures, pathologic examinations, and patient follow-up can vary greatly between different institutions, resulting in inevitable bias. In this retrospective study, we used a large cohort of patients who had undergone potentially curative surgery for ESCC at a single institution and confirmed the predictive ability of the 7th edition of the UICC-AJCC TNM staging system.
