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World J Gastroenterol. Dec 28, 2014; 20(48): 18092-18103
Published online Dec 28, 2014. doi: 10.3748/wjg.v20.i48.18092
Published online Dec 28, 2014. doi: 10.3748/wjg.v20.i48.18092
Fluid resuscitation in acute pancreatitis
Aakash Aggarwal, Department of Internal Medicine, SUNY Upstate, Syracuse, NY 13210, United States
Manish Manrai, Rakesh Kochhar, Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
Author contributions: Aggarwal A, Manrai M and Kochhar R wrote the paper; and Manrai M performed the literature review.
Correspondence to: Rakesh Kochhar, MD, Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Sector 12, Chandigarh 160012, India. dr_kochhar@hotmail.com
Telephone: +91-172-2756608 Fax: +91-172-2744401
Received: July 8, 2014
Revised: September 3, 2014
Accepted: October 14, 2014
Published online: December 28, 2014
Processing time: 181 Days and 14.1 Hours
Revised: September 3, 2014
Accepted: October 14, 2014
Published online: December 28, 2014
Processing time: 181 Days and 14.1 Hours
Core Tip
Core tip: Acute pancreatitis can manifest as a severe form, which has a high mortality rate. The treatment of AP is primarily supportive, and fluid replacement therapy has emerged as one of the key treatment strategies. There is a lack of randomized studies addressing the questions of the best type of fluid, amount of fluid and rate of fluid transfusion. This paper reviews the available literature and the controversies and attempts to frame guidelines for fluid therapy in acute pancreatitis.