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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 28, 2014; 20(44): 16750-16764
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16750
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16750
Laparoscopic vs open D2 gastrectomy for locally advanced gastric cancer: A meta-analysis
Zhen-Hong Zou, Department of General Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang 330006, Jiangxi Province, China
Li-Ying Zhao, Ting-Yu Mou, Yan-Feng Hu, Jiang Yu, Hao Liu, Hao Chen, Jia-Ming Wu, Guo-Xin Li, Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China
Sheng-Li An, Department of Biostatistics, Southern Medical University, Guangzhou 510515, Guangdong Province, China
Author contributions: Zou ZH and Zhao LY contributed equally to the bibliographic search, extraction of data, and preparation of the manuscript and should both be considered as co-first authors; Li GX and Yu J developed the concept and design of the study; Mou TY and An SL performed the analysis and interpretation of the data; Hu YF, Liu H, Chen H, and Wu JM reviewed the manuscript.
Correspondence to: Guo-Xin Li, MD, PhD, Professor, Department of General Surgery, Nanfang Hospital, Southern Medical University, No. 1838, North Guangzhou Avenue, Guangzhou 510515, Guangdong Province, China. gzliguoxin@163.com
Telephone: +86-20-61641683 Fax: +86-20-61641683
Received: March 17, 2014
Revised: May 9, 2014
Accepted: July 24, 2014
Published online: November 28, 2014
Revised: May 9, 2014
Accepted: July 24, 2014
Published online: November 28, 2014
Core Tip
Core tip: The Japanese Gastric Cancer Association guidelines stipulate that D2 gastrectomy is required for the treatment of advanced gastric cancer. Due to its technical difficulty and the lack of long-term results, the application of laparoscopic D2 gastrectomy (LGD2) remains questionable. Based on the results of this study, LGD2 had similar reoperation incidence, mortality, and oncologic outcomes compared with the open D2 gastrectomy for locally advanced gastric cancer treatment. Furthermore, LGD2 was associated with lower intraoperative blood loss, lower analgesic consumption, quicker recovery, shorter hospitalization, and lower morbidity, albeit with longer operative time.