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World J Gastroenterol. Nov 28, 2014; 20(44): 16739-16744
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16739
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16739
Xiaoyao pill for treatment of functional dyspepsia in perimenopausal women with depression
Han-Guang Du, Li Ming, Shu-Jiao Chen, Can-Dong Li, Research Base of Traditional Chinese Medicine Syndrome, Fujian University of Traditional Chinese Medicine, Fuzhou 350122, Fujian Province, China
Author contributions: Li CD, Du HG and Chen SJ designed the research; Du HG and Ming L analyzed the data; and Du HG and Ming L wrote the paper.
Supported by A grant from the National Physical Science Major Project, No. 81230087
Correspondence to: Can-Dong Li, MD, Professor, Research Base of Traditional Chinese Medicine Syndrome, Fujian University of Traditional Chinese Medicine, No. 1 Qiuyang Street, Fuzhou 350122, Fujian Province, China. fjzylcd@126.com
Telephone: +86-591-22861513 Fax: +86-591-22861513
Received: March 29, 2014
Revised: July 2, 2014
Accepted: July 24, 2014
Published online: November 28, 2014
Revised: July 2, 2014
Accepted: July 24, 2014
Published online: November 28, 2014
Core Tip
Core tip: This study observed the clinical effects of the Xiaoyao pill for treatment of perimenopausal women with functional dyspepsia (FD) and depression. The Xiaoyao pill improved patient symptoms as assessed by the Hamilton rating scale for depression and gastric emptying rate. The mechanism of these effects may be related to the observed increases in plasma motilin and gastrin levels, which can accelerate gastric emptying and improve propulsion through the small intestine.