Copyright
©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 28, 2014; 20(44): 16489-16497
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16489
Published online Nov 28, 2014. doi: 10.3748/wjg.v20.i44.16489
Microbiota alterations in acute and chronic gastrointestinal inflammation of cats and dogs
Julia B Honneffer, Yasushi Minamoto, Jan S Suchodolski, Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Science, Texas A & M University, College Station, TX 77843, United States
Author contributions: Honneffer JB, Minamoto Y, and Suchodolski JS contributed to this paper.
Correspondence to: Jan S Suchodolski, PhD, MedVet, DrMedVet, Diplomate ACVM, Gastrointestinal Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Science, Texas A & M University, 4474 TAMU, College Station, TX 77843-4474, United States. jsuchodolski@cvm.tamu.edu
Telephone: +1-979-4580933 Fax: +1-979-4584015
Received: April 29, 2014
Revised: July 4, 2014
Accepted: July 24, 2014
Published online: November 28, 2014
Revised: July 4, 2014
Accepted: July 24, 2014
Published online: November 28, 2014
Core Tip
Core tip: Several studies in dogs and cats have demonstrated that acute and chronic gastrointestinal diseases, including inflammatory bowel disease (IBD), are associated with alterations in the small intestinal and fecal microbial communities. Of interest is that these alterations are generally similar to the dysbiosis observed in humans with IBD or animal models of intestinal inflammation, suggesting that microbial responses in inflammatory conditions of the gut are conserved across mammalian host types, and dogs and cats may serve as models to study therapeutic approaches to spontaneous inflammatory conditions of the gastrointestinal tract.