Observational Study
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World J Gastroenterol. Nov 21, 2014; 20(43): 16293-16299
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16293
Functional gastrointestinal disorders in eating disorder patients: Altered distribution and predictors using ROME III compared to ROME II criteria
Xiaojie Wang, Georgina M Luscombe, Catherine Boyd, John Kellow, Suzanne Abraham
Xiaojie Wang, Catherine Boyd, Department of Obstetrics and Gynaecology, University of Sydney, NSW 2006, Australia
Georgina M Luscombe, School of Rural Health, University of Sydney, Orange, NSW 2800, Australia
John Kellow, Department of Gastroenterology and Medicine, University of Sydney, Royal North Shore Hospital, St Leonards, NSW 2065, Australia
Suzanne Abraham, Department of Obstetrics and Gynaecology, Northside Clinic, University of Sydney, Royal North Shore Hospital, NSW 2065, Australia
Author contributions: Wang X and Abraham S contributed to the design of the study; Boyd C perfomed the clinical research on the ROME II data; Wang X performed the clinical research on ROME III, data analyses and wrote the first draft; Luscombe GM contributed in statistical analyses; Wang X, Abraham S, Kellow J and Luscombe GM contributed to the interpretation of data, critical review of the article, and approved the final manuscript.
Correspondence to: Suzanne Abraham, Associate Professor, Department of Obstetrics and Gynaecology, University of Sydney, Building 52, Royal North Shore Hospital, St Leonards, NSW 2065, Australia. suzanne.abraham@sydney.edu.au
Telephone: +61-2-94629802 Fax: +61-2-94629802
Received: April 4, 2014
Revised: May 20, 2014
Accepted: June 21, 2014
Published online: November 21, 2014
Processing time: 230 Days and 7.6 Hours
Core Tip

Core tip: We compared the prevalence, behavioural and psychological predictors of functional gastrointestinal disorders using ROME III and ROME II questionnaires in two similar cohorts of eating disorder patients. We found the added timeframe requirement in ROME III added precision in diagnosing many Functional gastrointestinal disorders (FGIDs). We also found certain FGIDs in ROME III are predicted by eating behaviours and appear to have less psychological input compared to ROME II. These findings suggest that abnormal eating behaviours may play a more direct role in the disturbed physiology (both sensation and motility) of the gastrointestinal tract and hence the pathogenesis of certain FGIDs.