Pavri TM, Herbst A, Reddy R, Forde KA. Budd-Chiari syndrome: A single-center experience. World J Gastroenterol 2014; 20(43): 16236-16244 [PMID: PMC4239512 DOI: 10.3748/wjg.v20.i43.16236]
Corresponding Author of This Article
Kimberly A Forde, MD, MHS, Assistant Professor of Medicine and Epidemiology, Senior Scholar, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, 423 Guardian Drive, 722 Blockley Hall, Philadelphia, PA 19104, United States. kimberly.forde@uphs.upenn.edu
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Retrospective Study
Open-Access Policy of This Article
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World J Gastroenterol. Nov 21, 2014; 20(43): 16236-16244 Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16236
Budd-Chiari syndrome: A single-center experience
Tanya M Pavri, Alan Herbst, Rajender Reddy, Kimberly A Forde
Tanya M Pavri, Alan Herbst, Rajender Reddy, Kimberly A Forde, Division of Gastroenterology and Hepatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, United States
Kimberly A Forde, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, United States
Author contributions: Forde KA designed the research; Pavri TM and Herbst A performed the research and collected/recorded the data; Pavri TM, Forde KA and Reddy R analyzed the data; Pavri TM and Forde KA wrote the paper; all authors contributed to the critical revision of the manuscript and the approval of the final version of the manuscript submitted for publication.
Correspondence to: Kimberly A Forde, MD, MHS, Assistant Professor of Medicine and Epidemiology, Senior Scholar, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, 423 Guardian Drive, 722 Blockley Hall, Philadelphia, PA 19104, United States. kimberly.forde@uphs.upenn.edu
Telephone: +1-215-746-8597 Fax: +1-215-573-5325
Received: April 5, 2014 Revised: May 30, 2014 Accepted: July 11, 2014 Published online: November 21, 2014 Processing time: 229 Days and 20.2 Hours
Core Tip
Core tip: Budd-Chiari syndrome (BCS) is a challenging disease with a spectrum of clinical manifestations. It is evident from our experience that this condition has heterogeneous causes. Once specific prognostic factors are considered, treatment courses should be determined on a case-by-case basis but are most consistently instituted in a stepwise fashion. Moreover, in certain patients with visible hepatic decompensation, systemic anticoagulation may need to be fortified with portal decompression procedures such as transjugular intrahepatic portosystemic shunt earlier in the disease process. The liver transplant waitlist mortality was 15.6%; therefore, it is evident that BCS patients have high mortality despite being considered candidates for liver transplantation.
