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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 21, 2014; 20(43): 16113-16122
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16113
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16113
New tools for optimizing fluid resuscitation in acute pancreatitis
Perrine Bortolotti, Fabienne Saulnier, Delphine Colling, Sebastien Preau, Critical Care Center, University Hospital of Lille, 59037 Lille, France
Perrine Bortolotti, Fabienne Saulnier, Delphine Colling, Sebastien Preau, Laboratoire de Physiologie, EA 4484, Lille Nord de France University, 59037 Lille, France
Alban Redheuil, Cardiovascular Imaging, Pitié Salpêtrière Hospital Institute of Cardiology, 75013 Paris, France
Alban Redheuil, Sorbonne Universités, Laboratoire d’Imagerie Biomédicale, 75005 Paris, France
Alban Redheuil, Université Pierre et Marie Curie-Paris 6, 75005 Paris, France
Alban Redheuil, ICAN Imaging Core Lab, 75005 Paris, France
Author contributions: Bortolotti P and Preau S contributed equally to this work by performing literature search, writing and drafting the manuscript; Saulnier F, Colling D and Redheuil A carefully reviewed the submitted version.
Correspondence to: Sebastien Preau, MD, PhD, Critical Care Center, University Hospital of Lille, Avenue du Professeur Emile Laine, 59037 Lille, France. seb.preau@gmail.com
Telephone: +33-20-444084 Fax: +33-20-445094
Received: March 2, 2014
Revised: May 2, 2014
Accepted: June 12, 2014
Published online: November 21, 2014
Revised: May 2, 2014
Accepted: June 12, 2014
Published online: November 21, 2014
Core Tip
Core tip: Fluid therapy is a cornerstone of the early supportive treatment of acute pancreatitis. However, poor clinical evidence actually support the aggressive fluid therapy recommended in recent guidelines since available data are controversial. In this review, based on our experience of fluid management in the critically ill patients, we propose a tailored fluid administration relying on the individual benefit to risk balance, as a part of a global goal-directed hemodynamic strategy.