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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Nov 21, 2014; 20(43): 16101-16105
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16101
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16101
Enteral nutrition and immune modulation of acute pancreatitis
Refaat A Hegazi, Tiffany DeWitt, Research and development division, Abbott Nutrition, Columbus, OH 43219, United States
Author contributions: Hegazi RA and DeWitt T have been equally involved in reviewing the literature and writing the manuscript.
Correspondence to: Refaat A Hegazi, MD, PhD, MPH, MS, Medical Director Research and Development, Abbott Nutrition, 3300 Stelzer Rd, Columbus, OH 43219, United States. refaat.hegazi@abbott.com
Telephone: +1-614-6247811 Fax: +1-614-7277811
Received: March 1, 2014
Revised: May 9, 2014
Accepted: June 12, 2014
Published online: November 21, 2014
Processing time: 264 Days and 17 Hours
Revised: May 9, 2014
Accepted: June 12, 2014
Published online: November 21, 2014
Processing time: 264 Days and 17 Hours
Core Tip
Core tip: Due to the decreased food intake and increased nutrient requirements, patients with acute pancreatitis are at increased risk of malnutrition. Beyond meeting calorie and protein requirements, enteral nutrition exerts an immune modulating effect on the intestinal and systemic immune responses. Achieving the beneficial effects of enteral nutrition requires proper selection, placement and management of the feeding tubes and proper selection of the feeding formula. This review highlights new research of the immune effects of enteral nutrition, probiotics and prebiotics and suggests tools to help improve the patient adherence and tolerance to tube feeding.