Enteral nutrition and immune modulation of acute pancreatitis

doi:10.3748/wjg.v20.i43.16101

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Nov 21, 2014 (publication date) through May 1, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Nov 21, 2014; 20(43): 16101-16105
Published online Nov 21, 2014. doi: 10.3748/wjg.v20.i43.16101

Enteral nutrition and immune modulation of acute pancreatitis

Refaat A Hegazi, Tiffany DeWitt

Refaat A Hegazi, Tiffany DeWitt, Research and development division, Abbott Nutrition, Columbus, OH 43219, United States

Author contributions: Hegazi RA and DeWitt T have been equally involved in reviewing the literature and writing the manuscript.

Correspondence to: Refaat A Hegazi, MD, PhD, MPH, MS, Medical Director Research and Development, Abbott Nutrition, 3300 Stelzer Rd, Columbus, OH 43219, United States. refaat.hegazi@abbott.com

Telephone: +1-614-6247811 Fax: +1-614-7277811

Received: March 1, 2014
Revised: May 9, 2014
Accepted: June 12, 2014
Published online: November 21, 2014

Core Tip

Core tip: Due to the decreased food intake and increased nutrient requirements, patients with acute pancreatitis are at increased risk of malnutrition. Beyond meeting calorie and protein requirements, enteral nutrition exerts an immune modulating effect on the intestinal and systemic immune responses. Achieving the beneficial effects of enteral nutrition requires proper selection, placement and management of the feeding tubes and proper selection of the feeding formula. This review highlights new research of the immune effects of enteral nutrition, probiotics and prebiotics and suggests tools to help improve the patient adherence and tolerance to tube feeding.