Meta-Analysis
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World J Gastroenterol. Nov 14, 2014; 20(42): 15867-15878
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15867
Totally laparoscopic gastrectomy for gastric cancer: A systematic review and meta-analysis of outcomes compared with open surgery
Ke Chen, Yu Pan, Jia-Qin Cai, Xiao-Wu Xu, Di Wu, Yi-Ping Mou
Ke Chen, Yu Pan, Jia-Qin Cai, Xiao-Wu Xu, Di Wu, Yi-Ping Mou, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Author contributions: Chen K and Pan Y wrote the manuscript; Cai JQ, Xu XW and Wu D collected the literature and conducted the analysis of pooled data; Mou YP proofread and revised the manuscript; all authors approved the version to be published.
Supported by Zhejiang Key Subject of Medical Science Foundation, grant No.11-CX-21
Correspondence to: Yi-Ping Mou, MD, PhD, Professor, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. mouyiping2002@163.com
Telephone: +86-571-86006445 Fax: +86-571-86044817
Received: April 10, 2014
Revised: May 9, 2014
Accepted: June 13, 2014
Published online: November 14, 2014
Processing time: 221 Days and 5.1 Hours
Core Tip

Core tip: Laparoscopy-assisted gastrectomy for gastric cancer has rapidly become popular in the past decades due to its minimally invasive advantages over open gastrectomy (OG). However, totally laparoscopic gastrectomy (TLG) remains controversial in terms of safety and technical issues. This study evaluated the safety and efficacy of TLG compared with OG for gastric cancer by performing a systematic review and meta-analysis of the literature. The existing research shows that TLG is safe and feasible, and can achieve similar lymph node dissection effects to those of OG, and is characterized by advantages such as less pain, fewer postoperative complications, and rapid recovery, and is expected to achieve the same effect in oncological treatment as OG.