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World J Gastroenterol. Nov 14, 2014; 20(42): 15852-15859
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15852
Published online Nov 14, 2014. doi: 10.3748/wjg.v20.i42.15852
Perioperative restricted fluid therapy preserves immunological function in patients with colorectal cancer
Hong-Ying Jie, Ji-Lu Ye, Department of Intensive Care Unit, Taizhou People’s Hospital, Medical School of Nantong University, Taizhou 225300, Jiangsu Province, China
Hai-Hua Zhou, Department of General Surgery, Taizhou People’s Hospital, Medical School of Nantong University, Taizhou 225300, Jiangsu Province, China
Yun-Xiang Li, Department of Anesthesiology, Taizhou People’s Hospital, Medical School of Nantong University, Taizhou 225300, Jiangsu Province, China
Author contributions: Li YX, Jie HY and Ye JL designed the study; Jie HY, Zhou HH and Ye JL performed the study; Jie HY and Li YX analyzed the data; Jie HY and Li YX wrote and revised the paper.
Correspondence to: Yun-Xiang Li, MD, Department of Anesthesiology, Taizhou People’s Hospital, Medical School of Nantong University, No. 210 East Yingchun Road, Taizhou 225300, Jiangsu Province, China. drliyunxiang@163.com
Telephone: +86-523-86361607 Fax: +86-523-86361324
Received: April 10, 2014
Revised: June 8, 2014
Accepted: July 11, 2014
Published online: November 14, 2014
Revised: June 8, 2014
Accepted: July 11, 2014
Published online: November 14, 2014
Core Tip
Core tip: This prospective study revealed that perioperative restricted intravenous fluid regimen results in a low postoperative complication rate and better preservation of cellular immunity, which at least in part, explains the improved postoperative clinical outcomes associated with the restricted fluid regimen in patients with colorectal cancer.