Clinical management of advanced gastric cancer: The role of new molecular drugs

doi:10.3748/wjg.v20.i40.14537

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Oct 28, 2014 (publication date) through Nov 21, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Oct 28, 2014; 20(40): 14537-14558
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14537

Clinical management of advanced gastric cancer: The role of new molecular drugs

Ferdinando De Vita, Natale Di Martino, Alessio Fabozzi, Maria Maddalena Laterza, Jole Ventriglia, Beatrice Savastano, Angelica Petrillo, Valentina Gambardella, Vincenzo Sforza, Luigi Marano, Annamaria Auricchio, Gennaro Galizia, Fortunato Ciardiello, Michele Orditura

Ferdinando De Vita, Alessio Fabozzi, Maria Maddalena Laterza, Jole Ventriglia, Beatrice Savastano, Angelica Petrillo, Valentina Gambardella, Vincenzo Sforza, Fortunato Ciardiello, Michele Orditura, Division of Medical Oncology, Department of Clinical and Experimental Medicine and Surgery, Second University of Naples School of Medicine, 80131 Naples, Italy

Natale Di Martino, Luigi Marano, VIII General and Gastrointestinal Surgery, School of Medicine, Second University of Naples School of Medicine, 80138 Naples, Italy

Annamaria Auricchio, Gennaro Galizia, Divisions of Surgical Oncology, Department of Clinical and Experimental Medicine and Surgery, Second University of Naples School of Medicine, 80131 Naples, Italy

Author contributions: All the authors contributed equally to this manuscript.

Correspondence to: Dr. Ferdinando De Vita, MD, PhD, Assistant Professor of Oncology, Division of Medical Oncology, Department of Clinical and Experimental Medicine and Surgery, Second University of Naples School of Medicine, c/o II Policlinico, Edificio 3, Via Pansini 5, 80131 Naples, Italy. ferdinando.devita@unina2.it

Telephone: +39-81-5666713 Fax: +39-81-5666732

Received: October 29, 2013
Revised: February 19, 2014
Accepted: June 2, 2014
Published online: October 28, 2014
Processing time: 365 Days and 16.6 Hours

Core Tip

Core tip: In this article we review the actual “scenario” of targeted treatments in advanced gastric cancer, also focusing on the new agents in development,discussing their efficacy and potential applications in clinical practice.