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©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. Oct 28, 2014; 20(40): 14527-14536
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14527
Published online Oct 28, 2014. doi: 10.3748/wjg.v20.i40.14527
Evidence-based assessment of proton-pump inhibitors in Helicobacter pylori eradication: A systematic review
Vinayak Nagaraja, Guy D Eslick, The Whiteley-Martin Research Centre, Discipline of Surgery, The University of Sydney, Nepean Hospital, Penrith, NSW 2751, Australia
Author contributions: All authors contributed to this work.
Correspondence to: Guy D Eslick, Associate Professor, The Whiteley-Martin Research Centre, Discipline of Surgery, The University of Sydney, Nepean Hospital, Level 5, South Block, PO Box 63, Penrith, NSW 2751, Australia. guy.eslick@sydney.edu.au
Telephone: +61-2-47341373 Fax: +61-2-47343432
Received: October 11, 2013
Revised: May 15, 2014
Accepted: May 23, 2014
Published online: October 28, 2014
Processing time: 170 Days and 5.8 Hours
Revised: May 15, 2014
Accepted: May 23, 2014
Published online: October 28, 2014
Processing time: 170 Days and 5.8 Hours
Core Tip
Core tip: This review will discuss the different traits of treatment regimens for Helicobacter pylori (H. pylori)and will also give an insight about some unconventional and novel treatment strategies from a meta-analytic viewpoint. This review summarizes the recommendations and level of evidence regarding the role of the dose, type of proton-pump inhibitor, and the length of the treatment. The review also discusses the various regimes for second line therapy, sequential therapy and new alternate/adjuvant therapies for H. pylori therapy.