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©2014 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Jan 28, 2014; 20(4): 877-887
Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.877
Published online Jan 28, 2014. doi: 10.3748/wjg.v20.i4.877
Evolving treatment strategies for colorectal cancer: A critical review of current therapeutic options
Daniel C Damin, Division of Coloproctology, Department of Surgery, Hospital de Clinicas de Porto Alegre, Federal University of Rio Grande do Sul, Porto Alegre, RS 90035-903, Brazil
Anderson R Lazzaron, Postgraduate Program in Surgery, Federal University of Rio Grande do Sul, Porto Alegre, RS 90035-903, Brazil
Author contributions: Damin DC and Lazzaron AR contributed equally to this work by reviewing literature and writing the paper.
Correspondence to: Daniel C Damin, MD, PhD, Division of Coloproctology, Department of Surgery, Hospital de Clinicas de Porto Alegre, Federal University of Rio Grande do Sul, Rua Ramiro Barcelos 2350, Sala 600, Porto Alegre, RS 90035-903, Brazil. damin@terra.com.br
Telephone: +55-51-96020442 Fax: +55-51-33285168
Received: September 27, 2013
Revised: November 22, 2013
Accepted: January 6, 2014
Published online: January 28, 2014
Processing time: 121 Days and 17 Hours
Revised: November 22, 2013
Accepted: January 6, 2014
Published online: January 28, 2014
Processing time: 121 Days and 17 Hours
Core Tip
Core tip: Rectal cancer management is currently a multidisciplinary effort, which incorporates new concepts and technologies, resulting in significant improvement in patients’ oncological and functional outcomes. Despite the evolution reported in the last decades, there are still many unanswered questions about treatment of rectal cancer. In this article, we critically analyzed the main controversial matters in current rectal cancer management.