Clinical Trials Study
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World J Gastroenterol. Oct 7, 2014; 20(37): 13563-13572
Published online Oct 7, 2014. doi: 10.3748/wjg.v20.i37.13563
Factorial study of moxibustion in treatment of diarrhea-predominant irritable bowel syndrome
Ji-Meng Zhao, Lu-Yi Wu, Hui-Rong Liu, Hong-Yi Hu, Jia-Ying Wang, Ren-Jia Huang, Yin Shi, Shan-Ping Tao, Qiang Gao, Ci-Li Zhou, Li Qi, Xiao-Peng Ma, Huan-Gan Wu
Ji-Meng Zhao, Lu-Yi Wu, Hong-Yi Hu, Ren-Jia Huang, Jia-Ying Wang, Li Qi, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
Hui-Rong Liu, Yin Shi, Ci-Li Zhou, Xiao-Peng Ma, Huan-Gan Wu, Key Laboratory of Acupuncture-Moxibustion and Immunology, Shanghai Research Institute of Acupuncture and Meridian, Shanghai 200030, China
Jia-Ying Wang, Traditional Chinese Medicine Hospital of Shanxi Province, Taiyuan 030012, China
Shan-Ping Tao, Jiading Hospital of Traditional Chinese Medicine, Shanghai 201800, China
Qiang Gao, Jiading District Central Hospital, Shanghai 201800, China
Author contributions: Zhao JM, Wu LY, Liu HR and Hu HY have the same rights; Liu HR, Hu HY and Wu HG made the concept of the manuscript; Zhao JM, Wu LY, Huang RJ, Shi Y, Tao SP, Gao Q and Qi L collected the data; Wu LY, Wang JY, Zhou CL and Ma XP analysed the data; Zhao JM, Wu LY and Liu HR wrote the manuscript together; Zhao JM, Liu HR, Hu HY and Wu HG approved the final version of the manuscript.
Supported by National Basic Research Program of China (973 Program), No. 2009CB522900, 2009CB522901; Shanghai Top Clinical Medical Center of Acupuncture, Moxibustion and Tuina; and National Natural Sciences Foundation of China, Nos. 81303031 and 81202752
Correspondence to: Huan-Gan Wu, PhD, Key Laboratory of Acupuncture-Moxibustion and Immunology, Shanghai Research Institute of Acupuncture and Meridian, No.650 South Wanping Road, Xuhui District, Shanghai 200030, China. wuhuangan@126.com
Telephone: +86-21-64644238 Fax: +86-21-64644238
Received: May 16, 2014
Revised: June 11, 2014
Accepted: July 11, 2014
Published online: October 7, 2014
Processing time: 175 Days and 19.4 Hours
Core Tip

Core tip: This is a clinical factorial study focusing on aconite cake-separated moxibustion in the treatment of diarrhea-predominant irritable bowel syndrome. What is the effect of this ancient therapy on diarrhea-predominant irritable bowel syndrome patients? Which is the key factor in the treatment, the number of cones or the moxibustion frequency? This paper details answers to these questions.