Review
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World J Gastroenterol. Oct 7, 2014; 20(37): 13446-13452
Published online Oct 7, 2014. doi: 10.3748/wjg.v20.i37.13446
Stool characteristics of infants receiving short-chain galacto-oligosaccharides and long-chain fructo-oligosaccharides: A review
Petra AMJ Scholtens, Dominique AM Goossens, Annamaria Staiano
Petra AMJ Scholtens, Dominique AM Goossens, Nutricia Research, 3508 TC Utrecht, The Netherlands
Annamaria Staiano, Section of Pediatrics, Department of Translation Medical Science, Federico II, University of Naples, 80138 Naples, Italy
Author contributions: Scholtens PAMJ and Goossens DAM reviewed the relevant publications for this review; Scholtens PAMJ, Goossens DAM and Staiano A interpreted the data coming from the relevant publications; Scholtens PAMJ wrote the paper; Goossens DAM and Staiano A gave valuable input to the text.
Correspondence to: Dr. Petra AMJ Scholtens, Nutricia Research, PO Box 80141, 3508 TC Utrecht, The Netherlands. petra.scholtens@danone.com
Telephone: +31-30-2095000 Fax: +31-30-2100436
Received: February 12, 2014
Revised: May 9, 2014
Accepted: June 12, 2014
Published online: October 7, 2014
Core Tip

Core tip: In several clinical trials with a specific mixture of short-chain galacto-oligosaccharides and long-chain fructooligosaccharides in a ratio 9:1 in infant milk formulas, positive effects were observed on stool consistency and stool frequency. This specific mixture of short chain galacto-oligosaccharides and long-chain fructo-oligosaccharides may therefore have a role in reducing the risk of constipation.