Letters To The Editor
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World J Gastroenterol. Sep 21, 2014; 20(35): 12709-12710
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12709
May bacterial or pancreatic proteases play a critical role in inflammatory bowel disease?
Xiaofa Qin
Xiaofa Qin, GI Biopharma Inc, Westfield, NJ 07090, United States
Author contributions: Qin X is the sole author for this paper.
Correspondence to: Xiaofa Qin, MD, PhD, GI Biopharma Inc, 918 Willow Grove Road, Westfield, NJ 07090, United States. xiaofa_qin@yahoo.com
Telephone: +1-908-4637423 Fax: +1-908-6540654
Received: January 27, 2014
Revised: February 22, 2014
Accepted: April 21, 2014
Published online: September 21, 2014
Processing time: 235 Days and 19.3 Hours
Core Tip

Core tip: This is letter commenting on the paper by Carroll and Maharshak recently published in this journal regarding the role of enteric bacterial proteases in the pathogenesis of inflammatory bowel disease (IBD). Here I provide some evidence suggesting that the proteases originated from the pancreas rather than gut bacteria may have played a more critical role in the development of IBD.