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World J Gastroenterol. Sep 21, 2014; 20(35): 12662-12667
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12662
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12662
Association of autoimmune hepatitis and systemic lupus erythematodes: A case series and review of the literature
Claudia Beisel, Christina Weiler-Normann, Ansgar W Lohse, Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, 20246 Hamburg, Germany
Andreas Teufel, Department of Internal Medicine, Johannes Gutenberg Universität Mainz, 55122 Mainz, Germany
Andreas Teufel, Department of Internal Medicine, University Hospital Regensburg, 55122 Mainz, Germany
Author contributions: All authors participated in the diagnosis, management and follow-up of this clinical case and have reviewed, corrected and approved this final version of the manuscript.
Correspondence to: Claudia Beisel, MD, Department of Internal Medicine, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246 Hamburg, Germany. c.beisel@uke.de
Telephone: +49-40-741053910 Fax: +49-40-741058531
Received: March 18, 2014
Revised: May 18, 2014
Accepted: June 14, 2014
Published online: September 21, 2014
Processing time: 184 Days and 21 Hours
Revised: May 18, 2014
Accepted: June 14, 2014
Published online: September 21, 2014
Processing time: 184 Days and 21 Hours
Core Tip
Core tip: Hepatic involvement in patients with systemic lupus erythematodes (SLE) is considered to be rare. The differences between hepatic involvement caused by hepatotoxic drugs, coincident viral hepatitis, non-alcoholic fatty liver disease or concurrent autoimmune hepatitis (AIH) as independent disease has not been defined clearly in patients with SLE. This case report describes six patients who fulfill the current diagnostic criteria for both SLE and AIH, and thus represents the largest case series in the literature.