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World J Gastroenterol. Sep 21, 2014; 20(35): 12657-12661
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12657
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12657
Hepatoid adenocarcinoma of the colon in a patient with inflammatory bowel disease
Yuanyuan Chen, Eric M Yoshida, Division of Gastroenterology, University of British Columbia, Vancouver, BC V5Z 1M9, Canada
David F Schaeffer, Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V5Z 1M9, Canada
Author contributions: Chen Y drafted the article; Schaeffer DF obtained the pathologic background and data; Schaeffer DF and Yoshida EM critically revised the manuscript for intellectual content and approved the final version.
Correspondence to: Eric M Yoshida, MD, MHSc, FRCPC, Professor, Department Head, Division of Gastroenterology, University of British Columbia, 5th Floor, 2775 Laurel Street, Vancouver, BC V5Z 1M9, Canada. eric.yoshida@vch.ca
Telephone: +1-604-8755371 Fax: +1-604-8755447
Received: January 10, 2014
Revised: April 12, 2014
Accepted: May 12, 2014
Published online: September 21, 2014
Processing time: 252 Days and 1.8 Hours
Revised: April 12, 2014
Accepted: May 12, 2014
Published online: September 21, 2014
Processing time: 252 Days and 1.8 Hours
Core Tip
Core tip: This is the first reported case of a synchronous presentation of typical and hepatoid adenocarcinomata of the colon in a patient with long-standing ulcerative colitis and primary sclerosing cholangitis. This report addresses the clinical importance of probing for hepatoid adenocarcinomata in patients with increased serum alpha-fetoprotein levels in the absence of hepatocellular carcinoma.