Prospective Study
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World J Gastroenterol. Sep 21, 2014; 20(35): 12621-12627
Published online Sep 21, 2014. doi: 10.3748/wjg.v20.i35.12621
Optimal b value of diffusion-weighted imaging on a 3.0T magnetic resonance scanner in Crohn’s disease
Qi Feng, Yun-Qi Yan, Jiong Zhu, Jin-Lu Tong, Jian-Rong Xu
Qi Feng, Yun-Qi Yan, Jiong Zhu, Jian-Rong Xu, Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Jin-Lu Tong, Department of Gastroenterology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
Author contributions: Each author had participated sufficiently to take public responsibility for its content; Feng Q and Xu JR were guarantors of integrity of the entire study, and contributed to the study concepts and design; Feng Q and Zhu J contributed to the literature research; Tong JL contributed to the clinical studies; Feng Q and Yan YQ contributed to the experimental studies/data analysis; Feng Q prepared the manuscript; Xu JR contributed to the manuscript editing.
Supported by National Basic Research Program of China, No. 2012CB932600; and Shanghai Leading Academic Discipline Project, No. S30203
Correspondence to: Jian-Rong Xu, Director, Department of Radiology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, No. 1630, Dongfang Road, Pudong New District, Shanghai 200127, China. renjixujianrong@126.com
Telephone: +86-21-68383259 Fax: +86-21-50896639
Received: December 25, 2013
Revised: March 18, 2014
Accepted: June 14, 2014
Published online: September 21, 2014
Processing time: 264 Days and 4.6 Hours
Core Tip

Core tip: To date, nearly all the articles regarding diffusion-weighted imaging (DWI) utility in active Crohn’s disease chose relatively lower b values, and the examinations were finished on 1.5T magnetic resonance (MR) scanners. In our study, we try to investigate the appropriate b value of DWI on a high field MR scanner. During scanning, we adopted a low b value (800 s/mm2), a high b value (1500 s/mm2) and two very high b values (2000 and 2500 s/mm2). Our findings suggested that the b value of 1500 s/mm2 would be appropriate and when DWI was adopted on a 3.0T MR scanner, a high b value should be applied.