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World J Gastroenterol. Sep 14, 2014; 20(34): 12277-12282
Published online Sep 14, 2014. doi: 10.3748/wjg.v20.i34.12277
Published online Sep 14, 2014. doi: 10.3748/wjg.v20.i34.12277
Heartburn and regurgitation have different impacts on life quality of patients with gastroesophageal reflux disease
Shou-Wu Lee, Han-Chung Lien, Teng-Yu Lee, Sheng-Shun Yang, Hong-Jeh Yeh, Chi-Sen Chang, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung 40242, Taiwan
Shou-Wu Lee, Teng-Yu Lee, Chi-Sen Chang, Department of Medicine, Chung Shan Medical University, Taichung 40242, Taiwan
Han-Chung Lien, Sheng-Shun Yang, Hong-Jeh Yeh, Department of Medicine, Yang Ming University School of Medicine, Taipei 11217, Taiwan
Author contributions: Lee SW and Chang CS contributed equally to this work; Lee SW, Lien HC and Lee TY designed the research; Yang SS and Yeh HJ performed the research; Lee TY and Chang CS analyzed the data; and Lee SW and Lien HC wrote the paper.
Correspondence to: Shou-Wu Lee, MD, Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taichung Veterans General Hospital, No. 160, Sec. 3, Chung-Kang Rd., Taichung 40705, Taiwan. ericest429@yahoo.com.tw
Telephone: +886-4-23592525 Fax: +886-4-23595046
Received: January 23, 2014
Revised: April 9, 2014
Accepted: May 25, 2014
Published online: September 14, 2014
Revised: April 9, 2014
Accepted: May 25, 2014
Published online: September 14, 2014
Core Tip
Core tip: The study was aimed to investigate the impact of heartburn and regurgitation on the quality of life among patients with gastroesophageal reflux disease (GERD). The results found GERD patients with heartburn predominant had more severely impaired daily activities and lower general health scores than those with regurgitation predominant. Non-erosive reflux disease greatly impaired daily function in regurgitation-predominant patients, but did not have such impact in those with heartburn predominant.