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World J Gastroenterol. Aug 14, 2014; 20(30): 10564-10569
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10564
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10564
Chronic permanent hypoxemia predisposes to mild elevation of liver stiffness
Mohamed Tahiri, Yasmine Jalal, Wafaa Hliwa, Haddad Fouad, Wafaa Badre, Ahmad Bellabah, Rhimou Alaoui, Department of Gastroenterology, Ibn Rochd University Hospital Center of Casablanca, Casablanca 20170, Morocco
Abdenasser Drighil, Dounia Ghellab, Rachida Habal, Department of Cardiology, Ibn Rochd University Hospital Center of Casablanca, Casablanca 20170, Morocco
Author contributions: Tahiri M designed the research and wrote the paper; Jalal Y, Hliwa W, Fouad H, Badre W, Bellabah A and Alaoui R performed the research; Drighil A, Ghellab D and Habal R analyzed the data.
Correspondence to: Dr. Tahiri Mohame, PhD, Department of Gastroenterology, Ibn Rochd University Hospital Center of Casablanca, 187, Lotissement Madaronna, Sidi Maârouf, Casablanca 20170, Morocco. docteurtahirimohamed@yahoo.fr
Telephone: +212-77561214 Fax: +212-73618211
Received: August 22, 2013
Revised: October 31, 2013
Accepted: January 6, 2014
Published online: August 14, 2014
Processing time: 361 Days and 14.4 Hours
Revised: October 31, 2013
Accepted: January 6, 2014
Published online: August 14, 2014
Processing time: 361 Days and 14.4 Hours
Core Tip
Core tip: Our study is the first one to be carried out in humans and to evaluate the long term effect of hypoxemia on liver stiffness. The clinical model is provided by non operated adult patients with cyanotic cardiopathy. Heart failure, that can overestimate liver stiffness, is eliminated by echocardiography in all patients. The results show that long term hypoxemia leads to only mild liver stiffness elevation.