Retrospective Study
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World J Gastroenterol. Aug 14, 2014; 20(30): 10545-10552
Published online Aug 14, 2014. doi: 10.3748/wjg.v20.i30.10545
Risk factors associated with early and late HAT after adult liver transplantation
Yi Yang, Ji-Chun Zhao, Lu-Nan Yan, Yu-Kui Ma, Bin Huang, Ding Yuan, Bo Li, Tian-Fu Wen, Wen-Tao Wang, Ming-Qing Xu, Jia-Yin Yang
Yi Yang, Ji-Chun Zhao, Yu-Kui Ma, Bin Huang, Ding Yuan, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Lu-Nan Yan, Bo Li, Tian-Fu Wen, Wen-Tao Wang, Ming-Qing Xu, Jia-Yin Yang, Liver Transplantation Center, Department of Liver Surgery, West China Hospital, Sichuan University, Chengdu 610041, Sichuan Province, China
Author contributions: Yan LN and Zhao JC contributed equally to this work; Yan LN, Zhao JC and Yang Y designed the research; Zhao JC, Ma YK, Huang B, Yuan D and Yang Y contributed to the reconstruction of the hepatic artery; Li B, Wen TF, Wang WT, Xu MQ and Yang JY contributed to the clinical LT work; Yang Y wrote the manuscript; Zhao JC and Yan LN reviewed the manuscript.
Supported by Grants from the National Science and Technology Major Project of China, No. 2008ZX10002-026; and the National Science Foundation for Young Scientists of China, No. 81200226
Correspondence to: Ji-Chun Zhao, MD, PhD, Department of Vascular Surgery, Liver Transplantation Center, West China Hospital, Sichuan University, Guoxue Alley 37, Chengdu 610041, Sichuan Province, China. zhao_jc120@126.com
Telephone: +86-28-85422473 Fax: +86-28-85422473
Received: January 1, 2014
Revised: March 9, 2014
Accepted: April 15, 2014
Published online: August 14, 2014
Processing time: 228 Days and 17.6 Hours
Core Tip

Core tip: By analysing in detail the risk factors associated with early and late hepatic artery thrombosis (HAT) after adult liver transplantation (LT), we found factors that increased the risk for early and late HAT after LT, as well as some independent predictors of early and late HAT, particularly the postoperative use of blood transfusion which has not been mentioned in previous publications. For patients at increased risk for early and late HAT as described above, prophylactic anticoagulant treatment or daily surveillance by Doppler ultrasound could be considered for the possible prevention or early detection of HAT after LT.