Case Report
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World J Gastroenterol. Jan 21, 2014; 20(3): 857-862
Published online Jan 21, 2014. doi: 10.3748/wjg.v20.i3.857
Primary effusion lymphoma-like lymphoma in a patient with inflammatory bowel disease
Elchanan Nussinson, Fahmi Shibli, Azmi Shahbari, Wasseem Rock, Mazen Elias, Irit Elmalah
Elchanan Nussinson, Fahmi Shibli, Azmi Shahbari, Gastroenterology Institute, Emek Medical Center, Afula 18101, Israel
Wasseem Rock, Mazen Elias, Department of Internal Medicine C, Emek Medical Center, Afula 18101, Israel
Irit Elmalah, Department of Pathology, Emek Medical Center, Afula 18101, Israel
Author contributions: Nussinson E, Shibli F, Shahbari A, Rock W, Elias M and Elmalah I contributed to the conception and design of the study, data acquisition, and drafting of the article; all authors approved the final version of the manuscript.
Correspondence to: Elchanan Nussinson, MD, Gastroenterology Institute, Emek Medical Center, Duchifat 7 st’, Afula 18101, Israel. elchanann@gmail.com
Telephone: +972-5-44943922 Fax: +972-4-6495314
Received: July 8, 2013
Revised: September 2, 2013
Accepted: September 16, 2013
Published online: January 21, 2014
Processing time: 226 Days and 22.6 Hours
Core Tip

Core tip: We report a case of primary effusion lymphoma (PEL)-like lymphoma in an elderly, male inflammatory bowel disease (IBD) patient on 6-mercaptopurine (6-MP) treatment. This rare lymphoma subtype is localized to serous body cavities without tumor mass formation or nodal involvement, and has been previously reported in individuals with hepatitis C virus or Epstein-Barr virus infection, in patients who underwent organ transplantation, and elderly patients This novel case in an IBD patient illustrates the importance of considering PEL-like lymphoma in IBD patients treated with 6-MP and anti-tumor necrosis factor antibodies who subsequently develop serous body cavity effusion.