Review
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World J Gastroenterol. Aug 7, 2014; 20(29): 10008-10023
Published online Aug 7, 2014. doi: 10.3748/wjg.v20.i29.10008
Molecular pathology of intraductal papillary mucinous neoplasms of the pancreas
Marina Paini, Stefano Crippa, Stefano Partelli, Filippo Scopelliti, Domenico Tamburrino, Andrea Baldoni, Massimo Falconi
Marina Paini, Domenico Tamburrino, Department of Surgery, University of Verona, 37134 Verona (VR), Italy
Stefano Crippa, Stefano Partelli, Andrea Baldoni, Massimo Falconi, Division of Pancreatic Surgery, Ospedali Riuniti, Università Politecnica delle Marche, 60126 Ancona (AN), Italy
Filippo Scopelliti, Division of Pancreatic Surgery, Casa di Cura Dott. Pederzoli, 37019 Peschiera del Garda (VR), Italy
Author contributions: Paini M and Crippa S contributed equally to the paper; Paini M and Crippa S designed the research; Paini M, Crippa S, Partelli S, Scopelliti F, Tamburrino D and Baldoni A reviewed the literature and performed the review; Paini M and Crippa S wrote the paper; Falconi M reviewed all the work.
Correspondence to: Massimo Falconi, MD, Chief, Division of Pancreatic Surgery, Ospedali Riuniti, Università Politecnica delle Marche, Via Conca 71, 60126 Ancona (AN), Italy. m.falconi@univpm.it
Telephone: +39-71-5965781 Fax: +39-71-5964429
Received: December 10, 2013
Revised: March 4, 2014
Accepted: April 8, 2014
Published online: August 7, 2014
Processing time: 239 Days and 13.7 Hours
Core Tip

Core tip: The heterogeneity and the malignant potential of intraductal papillary mucinous neoplasms make their management still controversial. The identification of potential markers correlated to the pathogenesis of intraductal papillary mucinous neoplasms and with their progression to malignancy could be useful to discriminate lesions requiring surgical resection from benign neoplasms that could be followed-up.