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World J Gastroenterol. Jun 21, 2014; 20(23): 7473-7479
Published online Jun 21, 2014. doi: 10.3748/wjg.v20.i23.7473
Published online Jun 21, 2014. doi: 10.3748/wjg.v20.i23.7473
Clinical characteristics and corticosteroid therapy in patients with autoimmune-hepatitis-induced liver failure
Bing Zhu, Shao-Li You, Zhi-Hong Wan, Hong-Ling Liu, Yi-Hui Rong, Hong Zang, Shao-Jie Xin, Liver Failure Treatment and Research Center, 302nd Military Hospital, Beijing 100039, China
Author contributions: Zhu B, You SL and Wan ZH contributed equally to this work; Zhu B, You SL, Wan ZH and Xin SJ designed research; Zhu B, You SL, Liu HL, Rong YH and Zang H performed the research; Zhu B, You SL and Wan ZH analyzed the data and wrote the paper; all authors have read and approved the final manuscript.
Supported by Grants from the 12th Five-Year National Science and Technology Major Project for Infectious Diseases, No. 2012ZX10002004-005; 12th Five-Year Major Project of PLA, No. BWS11J075
Correspondence to: Shao-Jie Xin, Professor, Liver Failure Treatment and Research Center, 302nd Military Hospital, No. 100, Middle of West 4th Ring RD, Beijing 100039, China. xinshaojie302@163.com
Telephone: +86-10-66933433 Fax: +86-10-66933434
Received: December 3, 2013
Revised: February 25, 2014
Accepted: April 15, 2014
Published online: June 21, 2014
Processing time: 199 Days and 17.7 Hours
Revised: February 25, 2014
Accepted: April 15, 2014
Published online: June 21, 2014
Processing time: 199 Days and 17.7 Hours
Core Tip
Core tip: We describe the clinical characteristics and prognosis of autoimmune-hepatitis-induced liver failure in China. Early diagnosis and initiating corticosteroid therapy at an early stage may be essential for improving the prognosis of patients with AIH-induced liver failure without liver transplantation.