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World J Gastroenterol. May 28, 2014; 20(20): 6113-6122
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6113
Published online May 28, 2014. doi: 10.3748/wjg.v20.i20.6113
Role of surgery in colorectal cancer liver metastases
Özgür Akgül, Şiyar Ersöz, Mesut Tez, ErdinçÇetinkaya, Department of General Surgery, Ankara Numune Education and Research Hospital, 06100 Ankara, Turkey
Author contributions: Akgül Ö drafted the manuscript and approved the final manuscript; Çetinkaya E evaluated the English language of the paper and approved the final manuscript; Ersöz Ş helped with the literature search and approved the final manuscript; Tez M critically reviewed the manuscript, and approved the final manuscript.
Correspondence to: Mesut Tez, MD, Department of General Surgery, Ankara Numune Education and Research Hospital, Samanpazarı, 5.cadde 10/3 Bahçelievler, 06100 Ankara, Turkey. mesuttez@yahoo.com
Telephone: +90-312-5084052 Fax: +90-312-5084052
Received: October 28, 2013
Revised: December 26, 2013
Accepted: February 16, 2014
Published online: May 28, 2014
Processing time: 211 Days and 13.1 Hours
Revised: December 26, 2013
Accepted: February 16, 2014
Published online: May 28, 2014
Processing time: 211 Days and 13.1 Hours
Core Tip
Core tip: In patients with colorectal liver metastases, surgical resection is the treatment of choice. This paper aimed to discuss the goals of surgery, which should be to resect all metastases with negative histological margins while preserving sufficient functional hepatic parenchyma. The paper also discusses treatment options for patients with extensive metastatic disease who would otherwise be unresectable, such as systemic chemotherapy, radiofrequency ablation and preoperative portal vein embolization combined with surgery.