Copyright
©2014 Baishideng Publishing Group Inc. All rights reserved.
World J Gastroenterol. May 21, 2014; 20(19): 5903-5911
Published online May 21, 2014. doi: 10.3748/wjg.v20.i19.5903
Published online May 21, 2014. doi: 10.3748/wjg.v20.i19.5903
Histological changes of gastric mucosa after Helicobacter pylori eradication: A systematic review and meta-analysis
Yan-Jun Kong, Division of Traditional Chinese Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
Hong-Gang Yi, Jun-Cheng Dai, Division of Epidemiology, Nanjing Medical University School of Public Health, Nanjing 210029, Jiangsu Province, China
Mu-Xin Wei, Division of Traditional Chinese Medicine, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China
Mu-Xin Wei, National Institute for Physiological Sciences, Okazaki, Aichi 444-8585, Japan
Mu-Xin Wei, HiPep Laboratories, Kyoto 602-8158, Japan
Author contributions: Kong YJ collected the data and performed the meta-analysis; Dai JC and Yi HG participated in the retrieval of articles suitable for analysis; Wei MX provided guidance and proofread the manuscript.
Correspondence to: Mu-Xin Wei, Professor, Division of Traditional Chinese Medicine, the First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing 210029, Jiangsu Province, China. weimuxin@njmu.edu.cn
Telephone: +86-25-68136267 Fax: +86-25-83724440
Received: September 3, 2013
Revised: December 13, 2013
Accepted: January 8, 2014
Published online: May 21, 2014
Processing time: 256 Days and 23.9 Hours
Revised: December 13, 2013
Accepted: January 8, 2014
Published online: May 21, 2014
Processing time: 256 Days and 23.9 Hours
Core Tip
Core tip: This study reports the results of a meta-analysis conducted on a large number of articles using an extensive and thorough method. The inclusion of only high-quality relevant articles resulted in the identification of a very strong correlation between the eradication of Helicobacter pylori infection and intestinal metaplasia of the antrum, and a strong correlation with gastric atrophy in both the antrum and the corpus of the stomach.