Meta-Analysis
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World J Gastroenterol. May 14, 2014; 20(18): 5548-5556
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5548
Endoscopic papillary large balloon dilation vs endoscopic sphincterotomy for retrieval of common bile duct stones: A meta-analysis
Piao-Piao Jin, Jian-Feng Cheng, Dan Liu, Mei Mei, Zhao-Qi Xu, Lei-Min Sun
Piao-Piao Jin, Lei-Min Sun, Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Jian-Feng Cheng, Internal Medicine, Division of Gastroenterology, Carolinas Medical Center, Charlotte, NC 28203, United States
Dan Liu, Department of Statistics, Texas A and M University, College Station, TX 77843, United States
Mei Mei, Doppler Ultrasonic Department, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310016, Zhejiang Province, China
Zhao-Qi Xu, Fifth People’s Hospital of Yuhang District, Hangzhou 310016, Zhejiang Province, China
Author contributions: Jin PP designed the study, performed data analysis and drafted the manuscript as the first author; Cheng JF contributed to manuscript preparation, editing, revision and supervising the statistical analysis; Liu D revised the statistics and discussion; Mei M and Xu ZQ were responsible for data collection and analysis; Sun LM contributed to study design, discussion and edited the manuscript as the corresponding author.
Supported by Technology Foundation for Selected Overseas Chinese Scholar, Zhejiang Province, No. 188020-710903/016
Correspondence to: Lei-Min Sun, MD, PhD, Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, No. 3, East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. sunleimin@yahoo.com
Telephone: +86-571-86006186 Fax: +86-571-86044817
Received: October 10, 2013
Revised: March 2, 2014
Accepted: March 12, 2014
Published online: May 14, 2014
Processing time: 215 Days and 20.4 Hours
Core Tip

Core tip: Endoscopic papillary large balloon dilation (EPLBD) was as effective as endoscopic sphincterotomy in large common bile duct stone clearance. However, it had less requirement for endoscopic mechanical lithotripsy, even in stones larger than 15 mm. Besides, EPLBD could be conducted with limited or without precutting of the papilla which may be promising for application in patients with coagulopathy or with surgically modified anatomy. Further investigations are required to confirm this claim.