Yang SF, Liu BC, Ding WW, He CS, Wu XJ, Li JS. Initial transcatheter thrombolysis for acute superior mesenteric venous thrombosis. World J Gastroenterol 2014; 20(18): 5483-5492 [PMID: 24833878 DOI: 10.3748/wjg.v20.i18.5483]
Corresponding Author of This Article
Xing-Jiang Wu, MD, Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, No. 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China. wuxingjiang@sohu.com
Research Domain of This Article
Gastroenterology & Hepatology
Article-Type of This Article
Original Article
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Shuo-Fei Yang, Bao-Chen Liu, Wei-Wei Ding, Chang-Sheng He, Xing-Jiang Wu, Jie-Shou Li, Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing 210002, Jiangsu Province, China
Author contributions: Yang SF and Wu XJ designed the study and performed the data analysis and interpretation; Yang SF, Liu BC, Ding WW and He CS were the treating physicians; Yang SF and Liu BC performed the literature search; Yang SF wrote the manuscript; Wu XJ and Li JS revised the manuscript for critical intellectual content; all of the authors read and approved the final version of the manuscript.
Supported by Grants from the National Science Foundation of China, No. 81300278; the Natural Science Foundation of Jiangsu Province, No. BK20130697; and the Jiangsu Provincial Special Program of Medical Science, No. BL2012006
Correspondence to: Xing-Jiang Wu, MD, Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, No. 305 East Zhongshan Road, Nanjing 210002, Jiangsu Province, China. wuxingjiang@sohu.com
Telephone: +86-13-815429309 Fax: +86-25-84803956
Received: November 14, 2013 Revised: January 15, 2014 Accepted: February 20, 2014 Published online: May 14, 2014 Processing time: 181 Days and 1.9 Hours
Core Tip
Core tip: There is no consensus on the recommendation of initial management of acute superior mesenteric venous thrombosis (ASMVT) with moderate, circumscribed peritonitis and suspected bowel infarction. Signs of peritonitis have traditionally been considered an indicator for prompt surgery, but patients undergoing extensive bowel resection during an acute inflammatory phase frequently manifest short bowel syndrome. A non-operative treatment modality was recently developed to overcome this clinical challenge. Intravascular thrombolysis therapy has since been widely applied and favorable clinical outcomes have been reported. This study systematically investigates the outcome of transcatheter thrombolysis as a first-line treatment for ASMVT patients with circumscribed peritonitis.
