Review
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World J Gastroenterol. May 14, 2014; 20(18): 5461-5473
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5461
Helicobacter pylori associated chronic gastritis, clinical syndromes, precancerous lesions, and pathogenesis of gastric cancer development
Jiro Watari, Nancy Chen, Peter S Amenta, Hirokazu Fukui, Tadayuki Oshima, Toshihiko Tomita, Hiroto Miwa, Kheng-Jim Lim, Kiron M Das
Jiro Watari, Hirokazu Fukui, Tadayuki Oshima, Toshihiko Tomita, Hiroto Miwa, Division of Gastroenterology, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya 663-8501, Japan
Nancy Chen, Peter S Amenta, Kheng-Jim Lim, Kiron M Das, Division of Gastroenterology and Hepatology, Departments of Medicine and Pathology, Robert Wood Johnson Medical School, Rutgers, Cancer Institute of New Jersey, New Brunswick, NJ 08903, United States
Author contributions: Watari J drafted the initial manuscript; Chen N and Lim KJ contributed further and modified sequential draft; Amenta PS provided immunohistochemical interpretation for the various monoclonal antibodies; Das KM critically guided the format and content of the manuscript and revised the paper; all the contributed authors read and approved the final manuscript.
Supported by Grant, NIDDK, RO1DK63618 to KMD from the National Institutes of Health, Bethesda, MD
Correspondence to: Kiron M Das, MD, PhD, Division of Gastroenterology and Hepatology, Departments of Medicine and Pathology, Robert Wood Johnson Medical School, Rutgers, Cancer Institute of New Jersey, 1 Robert Wood Johnson Pl., New Brunswick, NJ 08903, United States. daskm@rwjms.rutgers.edu
Telephone: +81- 732-2357784 Fax: +81-732-2357792
Received: November 2, 2013
Revised: December 12, 2013
Accepted: March 7, 2014
Published online: May 14, 2014
Processing time: 193 Days and 6.5 Hours
Core Tip

Core tip: This review provides a current understanding on Helicobacter pylori, pathogenesis of chronic gastritis, gastric intestinal metaplasia, gastric carcinoma, and prevention strategy.