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World J Gastroenterol. May 14, 2014; 20(18): 5212-5225
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5212
Published online May 14, 2014. doi: 10.3748/wjg.v20.i18.5212
Brain-gut axis in the pathogenesis of Helicobacter pylori infection
Jacek Budzyński, Department of Gastroenterology, Vascular Diseases and Internal Medicine, Nicolaus Copernicus University, The Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-168 Bydgoszcz, Poland
Jacek Budzyński, Clinical Ward of Vascular Diseases and Internal Medicine, The Jan Biziel University Hospital No. 2, 85-168 Bydgoszcz, Poland
Maria Kłopocka, Department of Gastroenterological Nursing, Nicolaus Copernicus University, The Ludwik Rydygier Collegium Medicum in Bydgoszcz, 85-168 Bydgoszcz, Poland
Author contributions: Budzyński J conceived of and wrote the manuscript; Kłopocka M revised the manuscript; Budzyński J and Kłopocka M performed the literature review, wrote the paper and approved the final revised version.
Correspondence to: Jacek Budzyński, MD, PhD, Clinical Ward of Vascular Diseases and Internal Medicine, The Jan Biziel University Hospital No. 2, Ujejskiego 75 Street, 85-168 Bydgoszcz, Poland. budz@cps.pl
Telephone: +48-52-3655347 Fax: +48-52-3655347
Received: September 25, 2013
Revised: January 11, 2014
Accepted: January 19, 2014
Published online: May 14, 2014
Processing time: 231 Days and 5.4 Hours
Revised: January 11, 2014
Accepted: January 19, 2014
Published online: May 14, 2014
Processing time: 231 Days and 5.4 Hours
Core Tip
Core tip: This manuscript is the first review concerning the interplay between Helicobacter pylori (H. pylori) infection and the brain-gut axis. Data from relevant publications, including both human and animal studies, were grouped and discussed according to the pathophysiological mechanisms of interactions between H. pylori and host reaction.