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World J Gastroenterol. May 7, 2014; 20(17): 5036-5044
Published online May 7, 2014. doi: 10.3748/wjg.v20.i17.5036
Published online May 7, 2014. doi: 10.3748/wjg.v20.i17.5036
Ecological study of gastric cancer in Brazil: Geographic and time trend analysis
César Augusto Amorim, Antonio José Carneiro, Homero Soares Fogaça, Celeste Elia, Heitor Siffert Pereira de Souza, Serviço de Gastroenterologia, Departamento de Clínica Médica, Hospital Universitário, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-913, Brazil
Jéssica Pronestino Moreira, Luisa Rial, Ronir Raggio Luiz, Instituto de Epidemiologia e Saúde Coletiva, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ 21941-913, Brazil
Author contributions: Amorim CA, Carneiro AJ and Fogaça HS participated in the conception and design of the study, the acquisition, analysis, and interpretation of data, and the drafting of the manuscript; Moreira JP, Rial L and Elia C participated in the acquisition, analysis, and interpretation of the data and the drafting of parts of the manuscript; Luiz RR and de Souza HSP participated in the conception and design of the study, obtained funding, analyzed and interpreted data, and critically revised the manuscript for important intellectual content; all authors provided final approval of the submitted version of the manuscript.
Supported by The Brazilian Research Agencies CNPq and FAPERJ (financial support)
Correspondence to: Heitor Siffert Pereira de Souza, MD, Serviço de Gastroenterologia, Departamento de Clínica Médica, Hospital Universitário, Universidade Federal do Rio de Janeiro, Rua Prof. Rodolpho Paulo Rocco, 255, Ilha do Fundão, Rio de Janeiro, RJ 21941-913, Brazil. heitor.souza@gmail.com
Telephone: +55-21-25622669 Fax: +55-21-25622669
Received: October 11, 2013
Revised: January 4, 2014
Accepted: February 26, 2014
Published online: May 7, 2014
Revised: January 4, 2014
Accepted: February 26, 2014
Published online: May 7, 2014
Core Tip
Core tip: Declining rates in young patients and changes in the geographic distribution of gastric cancer suggest a recent decrease in the exposure to risk factors within the Brazilian environment.