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World J Gastroenterol. Mar 28, 2014; 20(12): 3059-3068
Published online Mar 28, 2014. doi: 10.3748/wjg.v20.i12.3059
New approaches for precise response evaluation in hepatocellular carcinoma
Koichi Hayano, Jorge M Fuentes-Orrego, Dushyant V Sahani
Koichi Hayano, Jorge M Fuentes-Orrego, Dushyant V Sahani, Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, United States
Author contributions: Hayano K and Sahani DV contributed to conception and design; Hayano K and Fuentes-Orrego JM contributed to manuscript writing and preparing figures and tables; Hayano K, Fuentes-Orrego JM and Sahani DV reviewed and approved this article to be published.
Correspondence to: Dushyant V Sahani, MD, Division of Abdominal Imaging and Intervention, Department of Radiology, Massachusetts General Hospital, 55 Fruit St, White 270, Boston, MA 02114, United States. dsahani@partners.org
Telephone: +1-617-7268361 Fax: +1-617-7264891
Received: September 28, 2013
Revised: November 26, 2013
Accepted: January 6, 2014
Published online: March 28, 2014
Processing time: 180 Days and 7.8 Hours
Core Tip

Core tip: Accurate tumor burden assessment is a critical component of patient management and the investigation of new therapies. With the increasing clinical use of novel biologic targeted agents or locoregional therapies, morphological analysis confronted limitations, and new methods to assess tumor burden were desired. Advances in imaging technique enable us to assess tumor functions such as viability, vascular physiology, or metabolism, which can be new approaches to assess tumor burden.