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©2014 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Mar 21, 2014; 20(11): 2854-2866
Published online Mar 21, 2014. doi: 10.3748/wjg.v20.i11.2854
Published online Mar 21, 2014. doi: 10.3748/wjg.v20.i11.2854
Non-invasive diagnosis of liver fibrosis in chronic hepatitis C
Leonardo de Lucca Schiavon, Janaína Luz Narciso-Schiavon, Gastroenterology Division, Department of Internal Medicine, Federal University of Santa Catarina, Florianópolis, SC 88040-900, Brazil
Roberto José de Carvalho-Filho, Gastroenterology Division, Department of Medicine, Federal University of Sao Paulo, Sao Paulo, SP 04023-900, Brazil
Author contributions: Schiavon LL, Narciso-Schiavon JL and Carvalho-Filho RJ contributed equally to this work, designed the review and wrote the paper.
Correspondence to: Leonardo de Lucca Schiavon, MD, PhD, Gastroenterology Division, Department of Internal Medicine, Federal University of Santa Catarina, 3 andar, Trindade, Florianópolis, SC 88040-900, Brazil. leo-jf@uol.com.br
Telephone: +55-48-37219149 Fax: +55-48-37219014
Received: October 29, 2013
Revised: December 10, 2013
Accepted: January 14, 2014
Published online: March 21, 2014
Revised: December 10, 2013
Accepted: January 14, 2014
Published online: March 21, 2014
Core Tip
Core tip: There is increased interest in non-invasive markers of fibrosis, especially in chronic hepatitis C virus infection. Although several methodologies have been proposed over the last few years, the limited availability and concerns regarding the true accuracy of these techniques has restricted their clinical application. In this review we will discuss the different noninvasive methods that are currently available for the evaluation of liver fibrosis in chronic hepatitis C, their advantages, limitations and application in clinical practice.