Published online Mar 14, 2014. doi: 10.3748/wjg.v20.i10.2731
Revised: November 12, 2013
Accepted: January 6, 2014
Published online: March 14, 2014
Processing time: 164 Days and 21.4 Hours
Core tip: We report a rare case of primary malignant melanoma of the esophagus (PMME). Although this disease is uncommon, a preoperative diagnosis of PMME is important. PMME cannot be definitely diagnosed from clinical symptoms or by X-ray barium meal examination but can be confirmed by endoscopic histological examination or a pathological report after surgical excision. The diagnosis of primary malignant melanoma should be suspected when a black or dark brown mass is observed during endoscopy. However, the endoscopic examination can complicate histological diagnosis due to poor sample quality. In the case presented here, we collected biopsies of the black surface, and the pathological report confirmed that the samples conformed to the characteristics of melanoma.