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©2014 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Mar 14, 2014; 20(10): 2725-2730
Published online Mar 14, 2014. doi: 10.3748/wjg.v20.i10.2725
Published online Mar 14, 2014. doi: 10.3748/wjg.v20.i10.2725
Huge undifferentiated carcinoma of the pancreas with osteoclast-like giant cells
Sungho Jo, Department of Surgery, Dankook University College of Medicine, Cheonan, Chungnam 330-714, South Korea
Author contributions: Jo S designed the research, performed the research, contributed new reagents/analytic tools, analyzed the data and wrote the manuscript.
Correspondence to: Sungho Jo, MD, Department of Surgery, Dankook University College of Medicine, 119, Dandae-ro, Dongnam-gu, Cheonan, Chungnam 330-714, South Korea. agapejsh@dankook.ac.kr
Telephone: +82-41-5503959 Fax: +82-41-5563878
Received: August 21, 2013
Revised: November 8, 2013
Accepted: November 28, 2013
Published online: March 14, 2014
Processing time: 202 Days and 21 Hours
Revised: November 8, 2013
Accepted: November 28, 2013
Published online: March 14, 2014
Processing time: 202 Days and 21 Hours
Core Tip
Core tip: Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (OGCs) is very rare and shows a poor prognosis. A 67-year female underwent subtotal pancreatectomy, total gastrectomy, and segmental resection of the transverse colon for a mass occupying the lesser sac and abutting the stomach and pancreas. Histopathological examination confirmed an 11cm-sized undifferentiated carcinoma of the pancreas with OGCs. The patient had suffered from multiple bone metastases and survived 9 mo after surgery. This case supports the ductal epithelial origin of undifferentiated carcinoma with OGCs and early diagnosis could result in favorable surgical outcomes.