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World J Gastroenterol. Feb 7, 2013; 19(5): 682-691
Published online Feb 7, 2013. doi: 10.3748/wjg.v19.i5.682
Published online Feb 7, 2013. doi: 10.3748/wjg.v19.i5.682
Interleukin-17 plays a critical role in the acute rejection of intestinal transplantation
Jian-Jun Yang, Fan Feng, Liu Hong, Li Sun, Meng-Bin Li, Wei-Zhong Wang, Guo-Sheng Wu, Hong-Wei Zhang, Department of Digestive Surgery, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China
Ran Zhuang, Department of Immunology, Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China
Feng Pan, Department of Medical Statistics, Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China
Ying-Mei Wang, Department of Pathology, Xijing Hospital, Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China
Author contributions: Yang JJ, Feng F, Hong L, and Sun L contributed equally to the work; Yang JJ and Feng F designed and performed all the animal experiments, and drafted the manuscript; Hong L assisted in in vivo animal experiments; Sun L assisted in biochemical experiments; Zhuang R assisted in immunological experiments; Wang YM assisted in hematoxylin eosin and immunofluorescence staining; Pan F assisted in experiment design, and carried out data collection and data analysis; Li MB, Wang WZ and Wu GS participated in human intestinal transplantation; Zhang HW, as director of the department, coordinated its execution and design, and revised the final version of the manuscript; all authors read and approved the present version of the manuscript.
Supported by Grants from Scientific Technology Research Development Project of Shaanxi in part, No. 2011K14-05-01, No. 2008K12-01; and a Grant from the National Natural Scientific Foundation of China, No. 31100643
Correspondence to: Hong-Wei Zhang, Professor, Department of Digestive Surgery, Xijing Hospital of Digestive Diseases, Fourth Military Medical University, Xi’an 710032, Shaanxi Province, China. hongwzh@126.com
Telephone: +86-29-84771507 Fax: +86-29-82539041
Received: September 13, 2012
Revised: December 11, 2012
Accepted: December 15, 2012
Published online: February 7, 2013
Revised: December 11, 2012
Accepted: December 15, 2012
Published online: February 7, 2013
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