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World J Gastroenterol. Dec 14, 2013; 19(46): 8752-8757
Published online Dec 14, 2013. doi: 10.3748/wjg.v19.i46.8752
Published online Dec 14, 2013. doi: 10.3748/wjg.v19.i46.8752
Perirenal space blocking restores gastrointestinal function in patients with severe acute pancreatitis
Jun-Jun Sun, Zhi-Jie Chu, Wei-Feng Liu, Shi-Fang Qi, Yan-Hui Yang, Peng-Lei Ge, Xiao-Hui Zhang, Wen-Sheng Li, Cheng Yang, Yu-Ming Zhang, Department of General Surgery, the First Affiliated Hospital of Henan University of Science and Technology, Luoyang 471003, Henan Province, China
Author contributions: Sun JJ designed the research; Chu ZJ, Liu WF and Qi SF performed the research; Yang YH, Ge PL and Zhang XH contributed new reagents or analytic tools; Li WS, Yang C and Zhang YM analyzed the data; Sun JJ and Chu ZJ wrote the paper.
Correspondence to: Jun-Jun Sun, Professor, Department of General Surgery, the First Affiliated Hospital of Henan University of Science and Technology, No. 24 JingHua Road, Luoyang 471003, Henan Province, China. junjunsuncn@126.com
Telephone: +86-379-64830650 Fax: +86-379-64830602
Received: May 29, 2013
Revised: October 21, 2013
Accepted: November 3, 2013
Published online: December 14, 2013
Processing time: 203 Days and 0.7 Hours
Revised: October 21, 2013
Accepted: November 3, 2013
Published online: December 14, 2013
Processing time: 203 Days and 0.7 Hours
Core Tip
Core tip: This work aims to investigate the effects of perirenal space blocking (PSB) on the gastrointestinal function and clinical outcome of patients with severe acute pancreatitis (SAP). Our results showed that PSB could commendably improve the gastrointestinal dysfunction or failure during the early stage of severe SAP. Moreover, PSB administration could improve prognosis and significantly decrease the hospital mortality of SAP patients.