Kekelidze M, D’Errico L, Pansini M, Tyndall A, Hohmann J. Colorectal cancer: Current imaging methods and future perspectives for the diagnosis, staging and therapeutic response evaluation. World J Gastroenterol 2013; 19(46): 8502-8514 [PMID: 24379567 DOI: 10.3748/wjg.v19.i46.8502]
Corresponding Author of This Article
Maka Kekelidze, MD, PhD, Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland. maka.kekelidze@usb.ch
Research Domain of This Article
Radiology, Nuclear Medicine & Medical Imaging
Article-Type of This Article
Topic Highlight
Open-Access Policy of This Article
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
World J Gastroenterol. Dec 14, 2013; 19(46): 8502-8514 Published online Dec 14, 2013. doi: 10.3748/wjg.v19.i46.8502
Colorectal cancer: Current imaging methods and future perspectives for the diagnosis, staging and therapeutic response evaluation
Maka Kekelidze, Luigia D’Errico, Michele Pansini, Anthony Tyndall, Joachim Hohmann
Maka Kekelidze, Luigia D’Errico, Michele Pansini, Anthony Tyndall, Joachim Hohmann, Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, 4031 Basel, Switzerland
Author contributions: Kekelidze M and Hohmann J designed and wrote the paper; D’Errico L contributed to the metastatic spreading part; Pansini M provided the images and contributed to posttreatment part; Tyndall A contributed to colonoscopy part; all authors revised the text for important intellectual content.
Correspondence to: Maka Kekelidze, MD, PhD, Clinic of Radiology and Nuclear Medicine, University Hospital Basel, University of Basel, Petersgraben 4, 4031 Basel, Switzerland. maka.kekelidze@usb.ch
Telephone: +41-61-3286567 Fax: +41-61-2655471
Received: September 30, 2013 Revised: November 6, 2013 Accepted: November 18, 2013 Published online: December 14, 2013
Core Tip
Core tip: This state-of-the-art review article covers current and future contribution of various imaging modalities in the diagnosis of colorectal cancer. Primary local staging, metastatic spread, restaging and posttreatment response evaluation are discussed in depth using emerging techniques such as virtual computed tomography (CT) colonoscopy, endorectal ultrasound and positron emission tomography/CT. The role and indications of more recently developed techniques as magnetic resonance imaging (MRI) with diffusion weighted images and hepatobiliary contrast materials are evaluated. The challenges and evolving role of functional imaging with MRI spectroscopy and hepatic transit time analysis using MRI and contrast enhanced ultrasound in the detection of liver metastases are also covered.
