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World J Gastroenterol. Dec 7, 2013; 19(45): 8349-8356
Published online Dec 7, 2013. doi: 10.3748/wjg.v19.i45.8349
Published online Dec 7, 2013. doi: 10.3748/wjg.v19.i45.8349
Association of visceral obesity and early colorectal neoplasia
Eun Kyung Choe, Department of Surgery, Healthcare Research Institute, Seoul National University Hospital, Healthcare System Gangnam Center, Seoul 135-984, South Korea
Donghee Kim, Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital, Healthcare System Gangnam Center, Seoul 135-984, South Korea
Hwa Jung Kim, Department of Clinical Epidemiology and Biostatistics, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, South Korea
Kyu Joo Park, Department of Surgery, Seoul National University College of Medicine, Seoul 110-799, South Korea
Author contributions: Kim D and Choe EK designed, and performed the research; Kim D and Kim HJ analyzed data and interpreted data; Choe EK, Kim D and Park KJ wrote the paper; all authors approved the final version
Supported by Grant from the Seoul National University Hospital Research Fund, No. 0420100610 (2010-1086)
Correspondence to: Donghee Kim, MD, PhD, Department of Internal Medicine, Healthcare Research Institute, Seoul National University Hospital, Healthcare System Gangnam Center, 39th FL., Gangnam Finance Center 737, Yeoksam-Dong, Gangnam-Gu, Seoul 135-984, South Korea. messmd@chol.com
Telephone: +82-2-21125500 Fax: +82-2-21125635
Received: August 5, 2013
Revised: September 3, 2013
Accepted: September 16, 2013
Published online: December 7, 2013
Processing time: 135 Days and 0.7 Hours
Revised: September 3, 2013
Accepted: September 16, 2013
Published online: December 7, 2013
Processing time: 135 Days and 0.7 Hours
Core Tip
Core tip: This study showed that visceral obesity is not a risk factor for early colorectal cancer, although it is an independent risk factor for colorectal adenoma in previous studies. Therefore, these data suggest that visceral obesity might influence the normal-adenoma sequence but not the adenoma-early carcinoma sequence.