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World J Gastroenterol. Dec 7, 2013; 19(45): 8247-8251
Published online Dec 7, 2013. doi: 10.3748/wjg.v19.i45.8247
Novel therapies for constipation
Sreedhari Thayalasekeran, Hani Ali, Her-Hsin Tsai
Sreedhari Thayalasekeran, Hani Ali, Her-Hsin Tsai, Department of Gastroenterology, Castle Hill Hospital, Cottingham HU165JQ, United Kingdom
Author contributions: Thayalasekeran S, Ali H and Tsai HH contributed equally to this work.
Correspondence to: Her-Hsin Tsai, MD, Department of Gastroenterology, Castle Hill Hospital, HEY NHS Trust, Cottingham HU165JQ, United Kingdom. hhtsai@doctors.org.uk
Telephone: +44-14-82875875 Fax: +44-14-82875875
Received: June 24, 2013
Revised: September 13, 2013
Accepted: October 13, 2013
Published online: December 7, 2013
Processing time: 176 Days and 16.3 Hours
Core Tip

Core tip: When standard laxatives fail in the management of constipation, licensed medication linaclotide and prucalopride show useful efficacy in clinical trials.