Case Report
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World J Gastroenterol. Nov 28, 2013; 19(44): 8151-8155
Published online Nov 28, 2013. doi: 10.3748/wjg.v19.i44.8151
Malignant paraganglioma of the rectum: The first case report and a review of the literature
Lin Yu, Jian Wang
Lin Yu, Jian Wang, Department of Pathology, Shanghai Cancer Center, Fudan University, Shanghai 200032, China
Lin Yu, Jian Wang, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China
Author contributions: Yu L designed and wrote the report; Wang J performed pathological diagnosis.
Correspondence to: Jian Wang, MD, Professor, Department of Pathology, Shanghai Cancer Center, Fudan University, 270 Dong An Road, Shanghai 200032, China. softtissuetumor@163.com
Telephone: +86-21-64175590 Fax: +86-21-64170067
Received: August 15, 2013
Revised: September 27, 2013
Accepted: October 13, 2013
Published online: November 28, 2013
Processing time: 116 Days and 2 Hours
Core Tip

Core tip: We report a rare case of malignant paraganglioma arising in the rectum of a 37-year-old male. To the best of our knowledge, the current case represents the first case of malignant paraganglioma arising in the rectum. Due to the unexpected occurrence in this region, rectal paraganglioma may be misdiagnosed as other common types of tumors with overlapping features; in particular, a neuroendocrine tumor of epithelial origin. Because of the differences in treatment, separating paraganglioma from its mimics is imperative.