Case Report
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World J Gastroenterol. Sep 21, 2013; 19(35): 5940-5942
Published online Sep 21, 2013. doi: 10.3748/wjg.v19.i35.5940
Obscure bleeding colonic duplication responds to proton pump inhibitor therapy
Jérémie Jacques, Fabrice Projetti, Romain Legros, Virginie Valgueblasse, Matthieu Sarabi, Paul Carrier, Fabien Fredon, Stéphane Bouvier, Véronique Loustaud-Ratti, Denis Sautereau
Jérémie Jacques, Fabrice Projetti, Romain Legros, Virginie Valgueblasse, Matthieu Sarabi, Paul Carrier, Fabien Fredon, Stéphane Bouvier, Véronique Loustaud-Ratti, Denis Sautereau, Service d’Hépato-gastro-entérologie, CHU Dupuytren, 87042 Limoges, France
Author contributions: Jacques J and Sautereau D reported this case; Jacques J and Loustaud-Ratti V wrote the paper; Jacques J, Legros R, Sarabi M, Carrier P and Valgueblasse V were attending doctors for the patient; Bouvier S and Fredon F performed the surgical operation; Projetti F performed pathological examinations.
Correspondence to: Jérémie Jacques, MD, Service d’Hépato-gastro-entérologie, CHU Dupuytren, Avenue Martin-Luther-King, 87042 Limoges, France. jeremiejacques@gmail.com
Telephone: +33-555-056631 Fax: +33-555-058733
Received: January 13, 2013
Revised: April 24, 2013
Accepted: May 17, 2013
Published online: September 21, 2013
Processing time: 250 Days and 14.3 Hours
Core Tip

Core tip: Obscure lower gastrointestinal bleeding is a difficult medical situation and potentially life threatening. The collaboration between endoscopists and radiologists usually allow location of the source of bleeding, but some rare situations, such as gastrointestinal malformations, need surgical intervention to diagnose and concomitantly treat an obscure bleeding source. In terms of medical therapy, only proton pump inhibitor therapy has efficacy in peptic ulcer disease. Obscure gastrointestinal bleeding responding to empiric antacid therapy should suggest the diagnosis of bleeding ectopic gastric mucosa such as Meckel’s diverticulum or gastrointestinal duplication, and gastroenterologists should be aware of this potential medical situation.