MicroRNA-21 as a potential colon and rectal cancer biomarker

doi:10.3748/wjg.v19.i34.5615

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Sep 14, 2013 (publication date) through Jun 19, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2013; 19(34): 5615-5621
Published online Sep 14, 2013. doi: 10.3748/wjg.v19.i34.5615

MicroRNA-21 as a potential colon and rectal cancer biomarker

Tao Li, Mei Ha Leong, Bruce Harms, Gregory Kennedy, Lin Chen

Tao Li, Mei Ha Leong, Lin Chen, Department of General Surgery, Chinese PLA General Hospital, Beijing 100853, China

Bruce Harms, Gregory Kennedy, Department of Surgery, University of Wisconsin Hospital, Madison, WI 53792, United States

Author contributions: All authors contributed equally to this work.

Correspondence to: Lin Chen, MD, PhD, Department of General Surgery, Chinese PLA General Hospital, 28 Fuxing Road Beijing 100853, China. chenlinbj@vip.sina.com

Telephone: +86-10-66938328 Fax: +86-10-66938028

Received: May 25, 2013
Revised: July 15, 2013
Accepted: July 18, 2013
Published online: September 14, 2013

Core Tip

Core tip: We summarize the latest study findings about microRNA-21 in colorectal cancer through a systematic review of literature. We recommend microRNA-21 as one of the most important microRNAs, which is rapidly emerging as a novel biomarker, with good potential as a diagnostic and therapeutic target.