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©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Sep 14, 2013; 19(34): 5615-5621
Published online Sep 14, 2013. doi: 10.3748/wjg.v19.i34.5615
Published online Sep 14, 2013. doi: 10.3748/wjg.v19.i34.5615
MicroRNA-21 as a potential colon and rectal cancer biomarker
Tao Li, Mei Ha Leong, Lin Chen, Department of General Surgery, Chinese PLA General Hospital, Beijing 100853, China
Bruce Harms, Gregory Kennedy, Department of Surgery, University of Wisconsin Hospital, Madison, WI 53792, United States
Author contributions: All authors contributed equally to this work.
Correspondence to: Lin Chen, MD, PhD, Department of General Surgery, Chinese PLA General Hospital, 28 Fuxing Road Beijing 100853, China. chenlinbj@vip.sina.com
Telephone: +86-10-66938328 Fax: +86-10-66938028
Received: May 25, 2013
Revised: July 15, 2013
Accepted: July 18, 2013
Published online: September 14, 2013
Processing time: 110 Days and 17.2 Hours
Revised: July 15, 2013
Accepted: July 18, 2013
Published online: September 14, 2013
Processing time: 110 Days and 17.2 Hours
Core Tip
Core tip: We summarize the latest study findings about microRNA-21 in colorectal cancer through a systematic review of literature. We recommend microRNA-21 as one of the most important microRNAs, which is rapidly emerging as a novel biomarker, with good potential as a diagnostic and therapeutic target.