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World J Gastroenterol. Aug 28, 2013; 19(32): 5365-5376
Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5365
Published online Aug 28, 2013. doi: 10.3748/wjg.v19.i32.5365
Systematic review and meta-analysis of laparoscopy-assisted and open total gastrectomy for gastric cancer
Ke Chen, Xiao-Wu Xu, Ren-Chao Zhang, Yu Pan, Di Wu, Yi-Ping Mou, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Zhejiang Province, China
Author contributions: Chen K and Xu XW wrote the manuscript; Zhang RC, Pan Y and Wu D collected literatures and conducted the analysis of pooled data; Mou YP proofread and revised the manuscript; all authors have approved the version to be published.
Supported by The key project grant from the Science and Technology Department of Zhejiang Province, China, No. 2011C3036-2
Correspondence to: Yi-Ping Mou, MD, PhD, Professor, Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, 3 East Qingchun Road, Hangzhou 310016, Zhejiang Province, China. mouyiping2002@163.com
Telephone: +86-571-86006445 Fax: +86-571-86044817
Received: March 29, 2013
Revised: May 23, 2013
Accepted: July 9, 2013
Published online: August 28, 2013
Processing time: 150 Days and 20.6 Hours
Revised: May 23, 2013
Accepted: July 9, 2013
Published online: August 28, 2013
Processing time: 150 Days and 20.6 Hours
Core Tip
Core tip: This study evaluated the safety and efficacy of laparoscopy-assisted total gastrectomy (LATG) and open total gastrectomy (OTG) for gastric cancer through systematic review and meta-analysis. The existing research shows that LATG is safe and feasible, which can achieve similar lymph node dissection effects as OTG, characterized by such advantages as less pain, fewer postoperative complications, and rapid recovery, and which is expected to achieve the same effect in oncological treatment as OTG.