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World J Gastroenterol. Aug 7, 2013; 19(29): 4791-4798
Published online Aug 7, 2013. doi: 10.3748/wjg.v19.i29.4791
Published online Aug 7, 2013. doi: 10.3748/wjg.v19.i29.4791
Stepwise sedation for elderly patients with mild/moderate COPD during upper gastrointestinal endoscopy
Can-Xia Xu, Xiong Chen, Yan Jia, Ding-Hua Xiao, Hui-Fang Zou, Qin Guo, Fen Wang, Xiao-Yan Wang, Shou-Rong Shen, Xiao-Ming Liu, Department of Gastroenterology, Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China
Ling-Ling Tong, Department of Health Statistics, University of South China, Hengyang 421001, Hunan Province, China
Ke Cao, Department of Oncology, Third Xiangya Hospital of Central South University, Changsha 410013, Hunan Province, China
Author contributions: Xu CX designed the study, performed the endoscopic procedures, analyzed the data, and wrote the manuscript; Chen X, Jia Y, Xiao DH, Zou HF, Guo Q, Wang F, Wang XY and Shen SR performed the endoscopic procedures; Tong LL, Cao K, and Liu XM analyzed the data.
Supported by A Grant from the National Natural Science Foundation of China, No. 81172301
Correspondence to: Can-Xia Xu, MD, Professor, Department of Gastroenterology, Third Xiangya Hospital of Central South University, 138 Tongzipo Street, Changsha 410013, Hunan Province, China. xucanxia2000@hotmail.com
Telephone: +86-731-88618631 Fax: +86-731-88618012
Received: March 28, 2013
Revised: July 2, 2013
Accepted: July 9, 2013
Published online: August 7, 2013
Processing time: 130 Days and 18.7 Hours
Revised: July 2, 2013
Accepted: July 9, 2013
Published online: August 7, 2013
Processing time: 130 Days and 18.7 Hours
Core Tip
Core tip: Many patients with chronic obstructive pulmonary disease (COPD) have to undergo upper gastrointestinal (GI) endoscopy because of digestive symptoms. A sedation method specially designed for elderly patients with COPD is urgently needed for use in clinical practice. In this study, we designed a new stepwise sedation method. Eighty-six elderly patients with COPD and 82 elderly patients without COPD scheduled for upper GI endoscopy were randomly assigned stepwise sedation or continuous sedation. The results indicate that the stepwise sedation method is effective and safer than the continuous sedation method for elderly patients with mild/moderate COPD during upper GI endoscopy.