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©2013 Baishideng Publishing Group Co., Limited. All rights reserved.
World J Gastroenterol. Jul 21, 2013; 19(27): 4374-4379
Published online Jul 21, 2013. doi: 10.3748/wjg.v19.i27.4374
Published online Jul 21, 2013. doi: 10.3748/wjg.v19.i27.4374
Predictive findings for Helicobacter pylori-uninfected, -infected and -eradicated gastric mucosa: Validation study
Kazuhiro Watanabe, Naoyoshi Nagata, Ryo Nakashima, Etsuko Furuhata, Masao Kobayakawa, Toshiyuki Sakurai, Koh Imbe, Ryota Niikura, Chizu Yokoi, Junichi Akiyama, Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Tokyo 162-8655, Japan
Takuro Shimbo, Department of Clinical Research and Informatics, National Center for Global Health and Medicine, Tokyo 162-8655, Japan
Naomi Uemura, Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, Kohnodai Hospital, Ichikawa City, Chiba 272-8516, Japan
Author contributions: Watanabe K collected clinical information and mainly wrote the manuscript; Shimbo T contributed to the statistical analysis; Nagata N and Akiyama J edited the manuscript; Kobayakawa M and Sakurai T performed the endoscopic assessments; Nakashima R, Furuhata E, Imbe K, Niikura R and Yokoi C helped with data acquisition; Nagata N and Uemura N designed the study.
Supported by A Grant from the National Center for Global Health and Medicine
Correspondence to: Dr. Naoyoshi Nagata, Department of Gastroenterology and Hepatology, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan. nnagata_ncgm@yahoo.co.jp
Telephone: +81-3-32027181 Fax: +81-3-32071038
Received: February 22, 2013
Revised: April 1, 2013
Accepted: May 18, 2013
Published online: July 21, 2013
Revised: April 1, 2013
Accepted: May 18, 2013
Published online: July 21, 2013
Core Tip
Core tip: To determine useful findings for predicting Helicobacter pylori (H. pylori)-uninfected, -infected, or -eradicated cases, we evaluated following 11 endoscopic findings, regular arrangement of collecting venules (RAC), linear erythema, hemorrhage, fundic gland polyp (FGP), atrophic change, rugal hyperplasia, edema, spotty erythema, exudate, xanthoma, and mottled patchy erythema (MPE). Among these, RAC, hemorrhage, FGP, atrophic change, and MPE were found to be predictive findings for H. pylori infection status on screening endoscopy. The knowledge of these findings may contribute to the early detection of gastric cancer.