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World J Gastroenterol. Jul 7, 2013; 19(25): 4083-4086
Published online Jul 7, 2013. doi: 10.3748/wjg.v19.i25.4083
Published online Jul 7, 2013. doi: 10.3748/wjg.v19.i25.4083
Azathioprine-induced fever in autoimmune hepatitis
Tawfik Khoury, Jacob E Ollech, Shmuel Chen, Meir Shalit, Departments of Internal Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, IL 91120, Israel
Meir Mizrahi, Departments of Gastroenterology and Hepatology, Gastroenterology and Liver Disease Institute, Hadassah-Hebrew University Medical Center, Jerusalem, IL 91120, Israel
Author contributions: Khoury T, Ollech JE, Chen S, Mizrahi M and Shalit M contributed equally to this paper.
Correspondence to: Meir Mizrahi, MD, Departments of Gastroenterology and Hepatology, Gastroenterology and Liver Disease Institute, Hadassah-Hebrew University Medical Center, Ein Kerem, POB 12000, Jerusalem, IL 91120, Israel. mizrahim@hadassah.org.il
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Received: September 22, 2012
Revised: February 26, 2013
Accepted: March 8, 2013
Published online: July 7, 2013
Revised: February 26, 2013
Accepted: March 8, 2013
Published online: July 7, 2013
Core Tip
Core tip: Azathioprine is widely used in inflammatory disease such as rheumatoid arthritis, inflammatory bowel disease and post solid organ transplant such as kidney transplantation. Azathioprine is an immune modulator drug that can expose patients to various infections and clinical fever. Azathioprine needs to be remembered as a potential fever provoker in the differential diagnosis of fever origin.