Brief Article
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World J Gastroenterol. Jul 7, 2013; 19(25): 4045-4052
Published online Jul 7, 2013. doi: 10.3748/wjg.v19.i25.4045
Recurrent abdominal liposarcoma: Analysis of 19 cases and prognostic factors
Wei Lu, James Lau, Mei-Dong Xu, Yong Zhang, Ying Jiang, Han-Xing Tong, Juan Zhu, Wei-Qi Lu, Xin-Yu Qin
Wei Lu, Mei-Dong Xu, Yong Zhang, Ying Jiang, Han-Xing Tong, Juan Zhu, Wei-Qi Lu, Xin-Yu Qin, General Surgery Department, Zhongshan Hospital, Fudan University, Shanghai 200032, China
James Lau, Department of Surgery, Stanford School of Medicine, Stanford, CA 94305, United States
Author contributions: Lu WQ and Qin XY designed the study concept; Xu MD, Zhang Y, Jiang Y, Tong HX and Zhu J were involved in patient data collection and statistical analysis; Lu W and Lau J wrote the manuscript.
Correspondence to: Wei-Qi Lu, MD, General Surgery Department, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China. lu.weiqi@zs-hospital.sh.cn
Telephone: +86-21-64041990 Fax: +86-21-64041990
Received: December 27, 2012
Revised: March 13, 2013
Accepted: March 23, 2013
Published online: July 7, 2013
Processing time: 191 Days and 2.2 Hours
Core Tip

Core tip: Recurrent abdominal liposarcoma (RAL) is an intractable disease encountered by both general surgeons and surgical oncologists. RAL commonly affects multiple organs, and re-operation for RAL is often difficult and is associated with significant risk, even when debulking is imminent. The high likelihood of postoperative complications and a lower survival outcome are detractors for repeat operations. A multidisciplinary team approach, realistic risk stratification, and careful management may help increase the success rate of gross total resection, lower these complication rates, improve survival, and increase the quality of life of these patients. Overall survival, relapse-free interval and other clinical follow-up data are also presented in detail in this study.